High school learning is generally divided into isolated subjects, with biology deemed rote learning and math as formulas with no practical value. In the data-driven digital age, high school students find it difficult to connect statistical or algebraic concepts to biological events like the spread of viruses and changes in ecosystems. Lack of connection between these fields reduces computational thinking and scientific literacy. This study examines whether the "Bio-Math Synergy" learning model improves high school students' transdisciplinary comprehension. The study used computerized techniques to incorporate ecology, genetics, function modeling, and basic statistics. This quasi-experimental study used pretest-posttest control groups. Eleventh graders from two Wajo Regency high schools studied. The experimental class utilized the "Bio-Math Synergy" model to analyze biology lab data through an interactive simulation platform and spreadsheets, while the control class employed traditional learning methods. The findings indicated the experimental class had much higher numeracy literacy results than the control class. Students learn that biology requires mathematics by modeling bacterial development and Mendel's rules digitally. Because STEM education felt more relevant to contemporary technology, an interest poll showed a 40% rise in student excitement for STEM jobs. This article provides a practical module for high school teachers to apply biology-math project-based learning (PjBL). This study supports digital-era education approaches that encourage critical thinking and cross-disciplinary problem-solving for Generation Z.
Downloads
- Abdi, G., Jain, M., Barwant, M., Tendulkar, R., Tendulkar, M., Tariq, M., & Amir, A. (2024). Unveiling the dynamic role of bioinformatics in automation for efficient and accurate data processing and interpretation. In Advances in Bioinformatics (pp. 279-319). Singapore: Springer Nature Singapore. https://doi.org/10.1007/978-981-99-8401-5_15
- Aini, V., Hidayat, T., Kusnadi, K., Williams, C., & Hadibarata, T. (2024). Analysis numeracy literacy skills of high school students in biodiversity material based on minimum competency assessment questions. Jurnal Pendidikan IPA Indonesia, 13(1), 128-136. https://doi.org/10.15294/jpii.v13i1.49265
- Almuhanna, M. A. (2025). Teachers' perspectives of integrating AI-powered technologies in K-12 education for creating customized learning materials and resources. Education and Information Technologies, 30(8), 10343-10371. https://doi.org/10.1007/s10639-024-13257-y
- Anđić, B., Lavicza, Z., Ulbrich, E., Cvjetićanin, S., Petrović, F., & Maričić, M. (2024). Contribution of 3D modelling and printing to learning in primary schools: a case study with visually impaired students from an inclusive Biology classroom. Journal of Biological Education, 58(4), 795-811. https://doi.org/10.1080/00219266.2022.2118352
- Bell, E., Provost, J., & Bell, J. K. (2019). Skills and foundational concepts for biochemistry students. In Biochemistry education: From theory to practice (pp. 65-109). American Chemical Society. https://doi.org/10.1021/bk-2019-1337.ch004
- Borovik, A. (2021). A mathematician’s view of the unreasonable ineffectiveness of mathematics in biology. Biosystems, 205, 104410. https://doi.org/10.1016/j.biosystems.2021.104410
- Christensen, D., & Lombardi, D. (2020). Understanding biological evolution through computational thinking: A K-12 learning progression. Science & Education, 29(4), 1035-1077. https://doi.org/10.1007/s11191-020-00141-7
- Clemson, M., Huang, A., Denyer, G., & Costabile, M. (2025). Teaching second‐year biochemistry students the principles of an enzyme‐catalyzed spectrophotometric assay with an online lab simulator. Biochemistry and Molecular Biology Education. https://doi.org/10.1002/bmb.21903
- Cornish-Bowden, A., & Hofmeyr, J. H. S. (2002). The role of stoichiometric analysis in studies of metabolism: an example. Journal of Theoretical Biology, 216(2), 179-191. https://doi.org/10.1006/jtbi.2002.2547
- dos Santos Carmo, J., & Crescenti, E. P. (2022). Mathematics anxiety and successful reversal strategies: A Brazilian experience. In Handbook of Stress and Academic Anxiety: Psychological Processes and Interventions with Students and Teachers (pp. 115-126). Cham: Springer International Publishing. https://doi.org/10.1007/978-3-031-12737-3_8
- Flanigan, A. E., & Babchuk, W. A. (2022). Digital distraction in the classroom: Exploring instructor perceptions and reactions. Teaching in Higher Education, 27(3), 352-370. https://doi.org/10.1080/13562517.2020.1724937
- Gordon, S. P., Gross, S., Bahamonde, M., Winn, J., Seifert, J., Martin, C. A., & Yang, Y. (2022). Developing a mathematics curriculum for the biosciences. Primus, 32(2), 218-245. https://doi.org/10.1080/10511970.2021.1919258
- Holmes, S. H., & Huber, W. (2018). Modern statistics for modern biology. Cambridge university press.
- Kantaros, A., Ganetsos, T., Pallis, E., & Papoutsidakis, M. (2025). From Mathematical Modeling and Simulation to Digital Twins: Bridging Theory and Digital Realities in Industry and Emerging Technologies. Applied Sciences, 15(16), 9213. https://doi.org/10.3390/app15169213
- Kokkonen, T., & Schalk, L. (2021). One instructional sequence fits all? A conceptual analysis of the applicability of concreteness fading in mathematics, physics, chemistry, and biology education. Educational Psychology Review, 33(3), 797-821. https://doi.org/10.1007/s10648-020-09581-7
- Lane, P. A. (2024). Robert Rosen’s relational biology theory and his emphasis on non-algorithmic approaches to living systems. Mathematics, 12(22), 3529. https://doi.org/10.3390/math12223529
- Marhami, M., Juandi, D., & Dasari, D. (2024). Indonesian students’ numeracy skills based on PISA mathematical problems in secondary school: A meta-synthesis. Jurnal Pendidikan MIPA, 25(1), 14-26. https://doi.org/10.23960/jpmipa/v25i1.pp14-26
- Martin, F., Long, S., Haywood, K., & Xie, K. (2025). Digital distractions in education: a systematic review of research on causes, consequences and prevention strategies. Educational technology research and development, 1-29. https://doi.org/10.1007/s11423-025-10550-6
- Megawati, L. A., & Sutarto, H. (2021). Analysis numeracy literacy skills in terms of standardized math problem on a minimum competency assessment. Unnes Journal of Mathematics Education, 10(2), 155-165. https://doi.org/10.15294/ujme.v10i2.49540
- Müller, F. A., & Wulf, T. (2024). Differences in learning effectiveness across management learning environments: A cognitive load theory perspective. Journal of Management Education, 48(4), 802-828. https://doi.org/10.1177/10525629231200206
- Nurqamar, D., & Nur, I. R. D. (2022). Comparative Study of Indonesian Students' Mathematical Literacy Abilities with Other Countries in Terms of PISA Type HOTS. EduMa: Mathematics education learning and teaching, 11(1), 45-56. http://dx.doi.org/10.24235/eduma.v11i1.9924
- Rozenszajn, R., & Yarden, A. (2014). Mathematics and biology teachers’ tacit views of the knowledge required for teaching: varying relationships between CK and PCK. International Journal of STEM Education, 1(1), 11. https://doi.org/10.1186/s40594-014-0011-7
- Shahidi Hamedani, S., Aslam, S., Mundher Oraibi, B. A., Wah, Y. B., & Shahidi Hamedani, S. (2024). Transitioning towards tomorrow’s workforce: Education 5.0 in the landscape of society 5.0: A systematic literature review. Education Sciences, 14(10), 1041. https://doi.org/10.3390/educsci14101041
- Shambare, B., & Simuja, C. (2022). A critical review of teaching with virtual lab: A panacea to challenges of conducting practical experiments in science subjects beyond the COVID-19 pandemic in rural schools in South Africa. Journal of Educational Technology Systems, 50(3), 393-408. https://doi.org/10.1177/00472395211058051
- Skulmowski, A., & Xu, K. M. (2022). Understanding cognitive load in digital and online learning: A new perspective on extraneous cognitive load. Educational psychology review, 34(1), 171-196. https://doi.org/10.1007/s10648-021-09624-7
- Sweller, J. (2020). Cognitive load theory and educational technology. Educational technology research and development, 68(1), 1-16. https://doi.org/10.1007/s11423-019-09701-3
- Tan, A. L., Ong, Y. S., Ng, Y. S., & Tan, J. H. J. (2023). STEM problem solving: Inquiry, concepts, and reasoning. Science & Education, 32(2), 381-397. https://doi.org/10.1007/s11191-021-00310-2
- Torre-Bastida, A. I., Diaz-de-Arcaya, J., Osaba, E., Muhammad, K., Camacho, D., & Del Ser, J. (2025). Bio-inspired computation for big data fusion, storage, processing, learning and visualization: state of the art and future directions. Neural Computing and Applications, 37(28), 23097-23127. https://doi.org/10.1007/s00521-021-06332-9
- Uitto, A., & Saloranta, S. (2017). Subject teachers as educators for sustainability: A survey study. Education Sciences, 7(1), 8. https://doi.org/10.3390/educsci7010008
- Weaver, K. F., Morales, V. C., Dunn, S. L., Godde, K., & Weaver, P. F. (2017). An introduction to statistical analysis in research: with applications in the biological and life sciences. John Wiley & Sons.
- Ziatdinov, R., Atteraya, M. S., & Nabiyev, R. (2024). The fifth industrial revolution as a transformative step towards society 5.0. Societies, 14(2), 19. https://doi.org/10.3390/soc14020019
Copyright (c) 2025 Fitri Fitri, Muhammad Hasbi

This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.
Most read articles by the same author(s)
- Muhammad Hasbi, Fitri Fitri, Ahmad Muktamar, Character Building Profile of Pancasila Students As An Effort to Realize National Character , ETDC: Indonesian Journal of Research and Educational Review : Vol. 2 No. 4 (2023): September
- Fitri Fitri, Muhammad Hasbi, The Relationship between Interest and Learning Motivation to Natural Science Learning Outcomes: A Narrative Review Study , ETDC: Indonesian Journal of Research and Educational Review : Vol. 4 No. 4 (2025): September
- Muhammad Hafeez, Muhammad Hasbi, All about learning methods: Past, Present and Future , ETDC: Indonesian Journal of Research and Educational Review : Vol. 2 No. 4 (2023): September
- Yusuf Razaq, Satriani Satriani, Amiruddin Amiruddin, Syamsul Bahri, Muhammad Hasbi, A Study Fable in Pair Work on ELT Learners' English Vocabulary Achievement , ETDC: Indonesian Journal of Research and Educational Review : Vol. 1 No. 3 (2022): June
- Djatmiko Hidajat, Muhammad Hasbi, Fitri Fitri, Metacognitive Skills of College Students in Mathematics Problem Solving: Overview by Student's Field Dependent , ETDC: Indonesian Journal of Research and Educational Review : Vol. 3 No. 2 (2024): March
- Fitri Fitri, The Impact of Reading Interest and Learning Habits on Students' Achievement for Integrated Science Learning , ETDC: Indonesian Journal of Research and Educational Review : Vol. 1 No. 4 (2022): September
- Satriani Satriani, Muhammad Hasbi, Yusuf Razaq, Nurul Muzkiyah, Ainun Fahira, Reciprocal Teaching Strategy on Reading Comprehension: A Review for Prospective Teachers , ETDC: Indonesian Journal of Research and Educational Review : Vol. 1 No. 2 (2022): March
- Muhammad Hasbi, Fitri Fitri, Realistic Mathematics Education and REACT Strategy in Context Mathematical Connections , ETDC: Indonesian Journal of Research and Educational Review : Vol. 3 No. 4 (2024): September
- Muhammad Hasbi, Fitri Fitri, Pre-Service Teachers with Courses in Problem-Based Learning in Mathematics , ETDC: Indonesian Journal of Research and Educational Review : Vol. 2 No. 2 (2023): March
- Fitri Fitri, Muhammad Hasbi, Ratna Ratna, Nadia Sudirman, Muh. Syakur, Dirmansyah Dirmansyah, Husnul Khatimah Annisa, Zahriyani Zahriyani, Muh. Fahri Khaeruddin, Classroom Management Strategies in Creating a Joyful Learning Environment in Madrasah Tsanawiyah , ETDC: Indonesian Journal of Research and Educational Review : Vol. 5 No. 2 (2026): March
Similar Articles
- Nurul Hudayanti Mahas, Besse Mutmainnah, Muhammad Ardi, Muh. Nasrullah Yusri, Rasma Rasma, Afriani Afriani, Muhammad Edwin, Dewi Marwah, Andi B. Daulat Samallangi, Andi Lutfia Qalbi, Educational Transformation as a Strategic Solution to Prevent Early Marriage: A Quantitative Study among Senior High School Students , ETDC: Indonesian Journal of Research and Educational Review : Vol. 5 No. 4 (2026): September
- Dhea Azar, Agus Pahrudin, Ida Faridatul Hasanah, Rudy Irawan, Fitriani Fitriani, Agus Susanti, Innovation in Aqidah Akhlak Learning: Implementing Think Pair Share to Cultivate Religious Moderation Values , ETDC: Indonesian Journal of Research and Educational Review : Vol. 5 No. 1 (2025): December
- Ishak Umar, Syamsu Qamar Badu, Putri Ekawaty Kobandaha, Analysis of Students' Mathematical Reasoning Abilities on Matrix Material at Senior High School , ETDC: Indonesian Journal of Research and Educational Review : Vol. 3 No. 4 (2024): September
- Romi Yanda, Istihana Istihana, Sunarto Sunarto, Optimizing Islamic and Character Education Outcomes Through Everyone is a Teacher Here (ETH) Learning Model , ETDC: Indonesian Journal of Research and Educational Review : Vol. 5 No. 3 (2026): June
- Saepul Saepul, Development of Animated Video Learning Media to Improve Students' Understanding of Ablution Procedures , ETDC: Indonesian Journal of Research and Educational Review : Vol. 3 No. 4 (2024): September
- Muh. Rani Rachmansyah Bachtiar, Kartini Kartini, Bulu’ Kanro, Promoting Student Tolerance via Religious Moderation: Evidence from Indonesian Multicultural High Schools , ETDC: Indonesian Journal of Research and Educational Review : Vol. 6 No. 1 (2026): September - December
- Mutiara Arlisyah Putri Utami, Taufiq Taufiq, Syaiful Syamsuddin, Entrepreneurial Intention Measurement Model in the Context of Assessment for Learning , ETDC: Indonesian Journal of Research and Educational Review : Vol. 5 No. 1 (2025): December
- Supratman Supratman, Andi Ihsan, Benny Badaru, Balance, Leg Power, and Motivation as Determinants of Shooting Skills in Islamic High School Football , ETDC: Indonesian Journal of Research and Educational Review : Vol. 5 No. 2 (2026): March
- Wardi Wardi, Hasbi Hasbi, Bustanul Iman RN, Co-Curricular Model Design in Overcoming Bullying Practices in Phase F Students in Senior High School , ETDC: Indonesian Journal of Research and Educational Review : Vol. 4 No. 4 (2025): September
- Fransiskus Saferius Nitit, Suwardi Suwardi, Suriah Hanafi, Application of Service Duel Approach to Improve High Secondary School Students' Badminton Backhand Serve Accuracy , ETDC: Indonesian Journal of Research and Educational Review : Vol. 6 No. 1 (2026): September - December
<< < 21 22 23 24 25 26 27 28 29 30 > >>
You may also start an advanced similarity search for this article.


















