Literature Study: Chemical Content and Benefits of Bidara Leaves (Ziziphus Muritiana) as an Indonesian Herbal
DOI:
https://doi.org/10.51574/hayyan.v1i2.1603Kata Kunci:
Bidara leaves, chemical content, traditional medicineAbstrak
Plants with various varieties can be found in various regions in Indonesia. Many varieties of medicinal plants in Indonesia have been used as raw materials for making medicines and several of these plant types have been clinically evaluated for their phytochemical composition, efficacy and safety of use. Bidara leaves, scientifically known as Zizhipus mauritiana L., are often used in Traditional Chinese Medicine to cure a number of diseases, such as urinary problems, digestive disorders, fever, liver complaints, weakness, anemia, obesity, diabetes, bronchitis, skin infections, loss of appetite. eating, pharyngitis, diarrhea, cancer, and insomnia. The reference literature obtained from the search results is then studied and examined to determine research findings, then described using the data or samples collected as is. Based on research and literature studies, bidara leaves have various significant health benefits, especially because of their rich chemical compound content. The flavonoid, tannin, terpenoid, steroid, alkaloid, triterpenoid and saponin compounds in bidara leaves have been proven to have anti-microbial, anti-depressant, anti-inflammatory, anti-oxidant and anti-cancer activity. Furthermore, bidara leaves can also protect body cells such as the kidneys and brain from oxidative stress, which is one of the main risk factors for cancer. Therefore, bidara leaves can be a safe and natural alternative treatment for various diseases and health conditions.
Referensi
Aisyah, N., Harahap, M., & Arfi, F. (2020). Phytochemical Analysis and Antibacterial Activity Test of Bidara Leaf Extract (Ziziphus mauritiana L.) against Esherichia coli and Staphylococcus aureus. AMINA, 2(3), 106–113.
AKHYAR, A. (2010). INHIBITION TESTING AND BIOAUTOGRAPHIC TLC ANALYSIS OF MANBAU ROOT AND FRUIT EXTRACTS (Rhizophora stylosa Griff.) AGAINST Vibrio harveyi (Doctoral dissertation, HASANUDDIN UNIVERSITY).
Ashri, N. (2016). TESTING THE ACTIVITY AND IDENTIFICATION OF ANTIBACTERIAL CHEMICAL COMPOUNDS FROM THE ETHANOLOUS EXTRACT OF LOTTERY LEAVES (Ziziphus spina-christi L) AGAINST SOME PATHOGEN BACTERIA.
Azizah, M. (2020). Antimicrobial activity of chitosan-coated chitosan-coated mango (Curcuma mangga) nanoparticles in vitro (Doctoral dissertation, Maulana Malik Ibrahim State Islamic University).
Bintoro, A., Ibrahim, AM, Situmeang, B., Kimia, JKSTA, & Cilegon, B. (2017). Analysis and identification of saponin compounds from bidara leaves (Zhizipus mauritania L.). Itekima Journal, 2(1), 84-94.
Chairunnisa, S., Wartini, N.M., & Suhendra, L. (2019). Effect of temperature and maceration time on the characteristics of bidara leaf extract (Ziziphus mauritiana L.) as a source of saponin. Journal of Agro-Industrial Engineering and Management ISSN, 2503, 488X.
EKANURSYAHFITRI, E. (2017). PHYSICAL QUALITIES AND ACTIVITY AGAINST THE BACTERIA Staphylococcus aureus PREPARATION OF A PEEL-OFF GEL MASK OF BIDDARA LEAF EXTRACT (Ziziphus mauritiana L.) AS ANTI ACNE (Doctoral dissertation, Putera Indonesia Malang Pharmacy Academy).
Haeria, H., & Andi, TU (2016). Determination of total flavonoid content and antioxidant activity of ethanol extract of bidara leaves (Ziziphus spina-christi L.). Journal of Pharmaceutical and Medicinal Science (1), 57-61.
Haeria, H., Dhuha, N., & Habra, R. (2018). Antibacterial Activity of Fractions of Bidara Leaves (Ziziphus mauritiana). ad-Dawaa'Journal of Pharmaceutical Sciences, 1(2).
Jannah, M. (2018). Test the anticancer activity of extracts and fractions of sea bidara leaves (Ziziphus mauritiana L.) against breast cancer cells (T47D) using the MTT method (Doctoral dissertation, Maulana Malik Ibrahim State Islamic University).
Junaidi, WS (2021). Formulation and Evaluation of Nanocream Preparations from Ethanol Extract of Bidara Leaves (Ziziphus mauritiana Lam.) as an Anti-Acne (Doctoral dissertation, University of North Sumatra).
KAMILA, K. (2019). EFFECTIVENESS OF UPAS BIDARA PLANT EXTRACT (Zizyphus spina-christi L) ON CONTROLLING THE BACTERIA Staphylococcus aureus (Doctoral dissertation, FKIP UNPAS).
Krisnawati, M. (2021). Physical Test and Antibacterial Activities of the Ethanol Cream Extract of Airleaf (Ziziphus Spina-Christi L.) on Propionibacterium Acnes ATCC 6919. Journal of Health, 8(2), 55-66.
Lumbanraja, IM, Wartini, NM, & Suhendra, L. (2019). The effect of solvent type and particle size on the characteristics of bidara leaf extract (Ziziphus mauritiana L.) as a source of saponin. Journal of Agro-Industrial Engineering and Management ISSN, 2503, 488X.
Magani, A. K., Tallei, T. E., & Kolondam, B. J. (2020). Antibacterial Test of Chitosan Nanoparticles on the Growth of Staphylococcus aureus and Escherichia coli Bacteria. Bios Logos Journal, 10(1), 7-12.
Nugrahwati, F. (2016). Antipyretic Activity Test of Bidara Leaf Extract (Ziziphus Spina-Christi L.) on Male Mice (Mus musculus). Faculty of Medicine and Health Sciences, Alauddin State Islamic University, Makassar.
Novia, NPH (2019). Test of the antidepressant activity of bidara leaf extract (Ziziphus mauritiana Lamk) on male white mice (Mus musculus) [thesis]. Setia Budi University Repository.
Nomer, NMGR, Duniaji, AS, & Nocianitri, KA (2019). the content of flavonoid and anthocyanin compounds in secang wood extract (Caesalpinia sappan L.) as well as antibacterial activity against Vibrio cholerae. Journal of Food Science and Technology, 8(2), 216-225.
Nusantari, M. (2015). POTENTIAL OF KATUK (Sauropus androgynus (L). Merr.) LEAF EXTRACT ON THE MICROBICIDAL ACTIVITY OF NEUTROPHIL CELLS EXPOSED TO Streptococcus mutans.
PABISA, M. (2020). TESTING THE ANTIBACTERIAL ACTIVITY OF ARAB LIVES LEAVE EXTRACT (Ziziphus spina-christi (L.) Desf.) AGAINST SOME PATHOGEN BACTERIA USING BIOAUTOGRAPHY TLC METHOD (Doctoral dissertation, Hasanuddin University).
Putri, RAZ (2017). Test the activity of Arabic bidara leaves (Ziziphus spina-christ l.) as anticancer in colon cancer cells (WiDr) using the MTT method and identify active compounds using the LC-MS method (Doctoral dissertation, Maulana Malik Ibrahim State Islamic University).
Rahmawati, Y. (2018). Surface Tension Test and Antioxidant Activity on Bidara Leaf Extract (Ziziphus mauritiana) (Doctoral dissertation, UIN Sunan Gunung Djati Bandung).
Rusdiana, Y., & Kurniawan, T.D. (2017). PHYSICAL QUALITY OF MIDWIFERE LEAF EXTRACT CREAM (Ziziphus mauritiana L.) USING VANISHING CREAM AND COLD CREAM BASE (Doctoral dissertation, Putera Indonesia Pharmacy Academy, Malang).
R.W., N. (2018). Test of the antioxidant and antidiabetic activity of the leaf extract fraction of bidara upas (Merremia mammosa (Lour) Hallier f.) [thesis]. Jember University Repository. March.
Sari, YA (2021). FORMULATION AND EVALUATION OF NANOCREAM PREPARATIONS OF ARGAN OIL (Argania spinosa L.) AS ANTI-AGING SKIN. University of Northern Sumatra.
Siregar, M. (2020). Various benefits of bidara leaves (Ziziphus mauritiana Lamk) for health in Indonesia: Meta analysis. Pandu Husada Journal, 1(2), 75-81.
Tazkiatulmilla, S. (2021). Formulation of Mouthwash Preparations from Bidara Leaf Extract (Ziziphus mauritiana Lam.) as an antifungal for Candida albicans which causes mouth ulcers (Doctoral dissertation, Thesis, Muhammadiyah University of Magelang).
Wahyudi, W., Hsb, HLP, Hasanan, N., & Sitorus, RAH (2022). Literature Study: Bidara Leaves (Ziziphus Mauritiana) as an Indonesian Herbal with Various Contents and Pharmacological Effectiveness. Journal of Pharmanesia, 9(1), 22-27.
AKHYAR, A. (2010). INHIBITION TESTING AND BIOAUTOGRAPHIC TLC ANALYSIS OF MANBAU ROOT AND FRUIT EXTRACTS (Rhizophora stylosa Griff.) AGAINST Vibrio harveyi (Doctoral dissertation, HASANUDDIN UNIVERSITY).
Ashri, N. (2016). TESTING THE ACTIVITY AND IDENTIFICATION OF ANTIBACTERIAL CHEMICAL COMPOUNDS FROM THE ETHANOLOUS EXTRACT OF LOTTERY LEAVES (Ziziphus spina-christi L) AGAINST SOME PATHOGEN BACTERIA.
Azizah, M. (2020). Antimicrobial activity of chitosan-coated chitosan-coated mango (Curcuma mangga) nanoparticles in vitro (Doctoral dissertation, Maulana Malik Ibrahim State Islamic University).
Bintoro, A., Ibrahim, AM, Situmeang, B., Kimia, JKSTA, & Cilegon, B. (2017). Analysis and identification of saponin compounds from bidara leaves (Zhizipus mauritania L.). Itekima Journal, 2(1), 84-94.
Chairunnisa, S., Wartini, N.M., & Suhendra, L. (2019). Effect of temperature and maceration time on the characteristics of bidara leaf extract (Ziziphus mauritiana L.) as a source of saponin. Journal of Agro-Industrial Engineering and Management ISSN, 2503, 488X.
EKANURSYAHFITRI, E. (2017). PHYSICAL QUALITIES AND ACTIVITY AGAINST THE BACTERIA Staphylococcus aureus PREPARATION OF A PEEL-OFF GEL MASK OF BIDDARA LEAF EXTRACT (Ziziphus mauritiana L.) AS ANTI ACNE (Doctoral dissertation, Putera Indonesia Malang Pharmacy Academy).
Haeria, H., & Andi, TU (2016). Determination of total flavonoid content and antioxidant activity of ethanol extract of bidara leaves (Ziziphus spina-christi L.). Journal of Pharmaceutical and Medicinal Science (1), 57-61.
Haeria, H., Dhuha, N., & Habra, R. (2018). Antibacterial Activity of Fractions of Bidara Leaves (Ziziphus mauritiana). ad-Dawaa'Journal of Pharmaceutical Sciences, 1(2).
Jannah, M. (2018). Test the anticancer activity of extracts and fractions of sea bidara leaves (Ziziphus mauritiana L.) against breast cancer cells (T47D) using the MTT method (Doctoral dissertation, Maulana Malik Ibrahim State Islamic University).
Junaidi, WS (2021). Formulation and Evaluation of Nanocream Preparations from Ethanol Extract of Bidara Leaves (Ziziphus mauritiana Lam.) as an Anti-Acne (Doctoral dissertation, University of North Sumatra).
KAMILA, K. (2019). EFFECTIVENESS OF UPAS BIDARA PLANT EXTRACT (Zizyphus spina-christi L) ON CONTROLLING THE BACTERIA Staphylococcus aureus (Doctoral dissertation, FKIP UNPAS).
Krisnawati, M. (2021). Physical Test and Antibacterial Activities of the Ethanol Cream Extract of Airleaf (Ziziphus Spina-Christi L.) on Propionibacterium Acnes ATCC 6919. Journal of Health, 8(2), 55-66.
Lumbanraja, IM, Wartini, NM, & Suhendra, L. (2019). The effect of solvent type and particle size on the characteristics of bidara leaf extract (Ziziphus mauritiana L.) as a source of saponin. Journal of Agro-Industrial Engineering and Management ISSN, 2503, 488X.
Magani, A. K., Tallei, T. E., & Kolondam, B. J. (2020). Antibacterial Test of Chitosan Nanoparticles on the Growth of Staphylococcus aureus and Escherichia coli Bacteria. Bios Logos Journal, 10(1), 7-12.
Nugrahwati, F. (2016). Antipyretic Activity Test of Bidara Leaf Extract (Ziziphus Spina-Christi L.) on Male Mice (Mus musculus). Faculty of Medicine and Health Sciences, Alauddin State Islamic University, Makassar.
Novia, NPH (2019). Test of the antidepressant activity of bidara leaf extract (Ziziphus mauritiana Lamk) on male white mice (Mus musculus) [thesis]. Setia Budi University Repository.
Nomer, NMGR, Duniaji, AS, & Nocianitri, KA (2019). the content of flavonoid and anthocyanin compounds in secang wood extract (Caesalpinia sappan L.) as well as antibacterial activity against Vibrio cholerae. Journal of Food Science and Technology, 8(2), 216-225.
Nusantari, M. (2015). POTENTIAL OF KATUK (Sauropus androgynus (L). Merr.) LEAF EXTRACT ON THE MICROBICIDAL ACTIVITY OF NEUTROPHIL CELLS EXPOSED TO Streptococcus mutans.
PABISA, M. (2020). TESTING THE ANTIBACTERIAL ACTIVITY OF ARAB LIVES LEAVE EXTRACT (Ziziphus spina-christi (L.) Desf.) AGAINST SOME PATHOGEN BACTERIA USING BIOAUTOGRAPHY TLC METHOD (Doctoral dissertation, Hasanuddin University).
Putri, RAZ (2017). Test the activity of Arabic bidara leaves (Ziziphus spina-christ l.) as anticancer in colon cancer cells (WiDr) using the MTT method and identify active compounds using the LC-MS method (Doctoral dissertation, Maulana Malik Ibrahim State Islamic University).
Rahmawati, Y. (2018). Surface Tension Test and Antioxidant Activity on Bidara Leaf Extract (Ziziphus mauritiana) (Doctoral dissertation, UIN Sunan Gunung Djati Bandung).
Rusdiana, Y., & Kurniawan, T.D. (2017). PHYSICAL QUALITY OF MIDWIFERE LEAF EXTRACT CREAM (Ziziphus mauritiana L.) USING VANISHING CREAM AND COLD CREAM BASE (Doctoral dissertation, Putera Indonesia Pharmacy Academy, Malang).
R.W., N. (2018). Test of the antioxidant and antidiabetic activity of the leaf extract fraction of bidara upas (Merremia mammosa (Lour) Hallier f.) [thesis]. Jember University Repository. March.
Sari, YA (2021). FORMULATION AND EVALUATION OF NANOCREAM PREPARATIONS OF ARGAN OIL (Argania spinosa L.) AS ANTI-AGING SKIN. University of Northern Sumatra.
Siregar, M. (2020). Various benefits of bidara leaves (Ziziphus mauritiana Lamk) for health in Indonesia: Meta analysis. Pandu Husada Journal, 1(2), 75-81.
Tazkiatulmilla, S. (2021). Formulation of Mouthwash Preparations from Bidara Leaf Extract (Ziziphus mauritiana Lam.) as an antifungal for Candida albicans which causes mouth ulcers (Doctoral dissertation, Thesis, Muhammadiyah University of Magelang).
Wahyudi, W., Hsb, HLP, Hasanan, N., & Sitorus, RAH (2022). Literature Study: Bidara Leaves (Ziziphus Mauritiana) as an Indonesian Herbal with Various Contents and Pharmacological Effectiveness. Journal of Pharmanesia, 9(1), 22-27.
