Caulerpin: Biosynthetic Significance and Cytotoxic Activity Against Artemia salina Leach
DOI:
https://doi.org/10.51574/hayyan.v2i2.3261Keywords:
Caulerpin, Halimeda, CaulerpaAbstract
Caulerpin (1) is one of the bisindole alkaloid compounds isolated from the many macroalga species of the Halimeda and Caulerpa genera. The biosynthetic significance of 1 is suggested by the biotransformation of indole-3-acetic acid to indole-3-carboxaldehyde via tryptophan from the shikimate pathway. This compound has many biological activities reported and this time, the 1 were evaluated for their cytotoxicity in the brine shrimp assay against A. salina Leach. in vitro and showed moderate activity with IC50 value 81.28 µg/mL.
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http://repository.unhas.ac.id:443/id/eprint/32741
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